RGS14 Protein (His tag)

Produktnummer ABIN6386992

Produktdetails

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses RGS14 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 80 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: regulator of G-protein signaling 14

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer, pH7.5, 10% glycerol, 1 MM DTT, 200 mM NaCl

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Andere Bezeichnung: RGS14 (RGS14 Produkte)

Synonyme: RPIP1 Protein, MGC80558 Protein, RGS14 Protein, rgs14 Protein, wu:fi04g12 Protein, regulator of G protein signaling 14 Protein, regulator of G-protein signaling 14 Protein, regulator of G-protein signaling 14 L homeolog Protein, regulator of G-protein signalling 14 Protein, regulator of G protein signaling 14a Protein, RGS14 Protein, Rgs14 Protein, rgs14.L Protein, rgs14 Protein, rgs14a Protein

Hintergrund: RGS14 (Regulator of G-protein signaling 14) belongs to regulator of G protein signalling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco motif. RGS14 is highly enriched in CA2 pyramidal neurons and plays a role in suppression of both synaptic plasticity at these synapses and hippocampal-based learning and memory. RGS14 is a scaffolding protein that integrates G protein and H-Ras/ERK/MAP kinase signaling pathways, thereby making it well positioned to suppress plasticity in CA2 neurons. Recombinant human RGS14 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 63.6kDa (586aa)

NCBI Accession: NP_006471

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling