RGS14 Produkte
(Regulator of G-Protein Signaling 14 (RGS14))
Kategorien
This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].
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Ausgewählte RGS14 Kategorien
RGS14 Antikörper
High quality antibodies with extensive validation data.
RGS14 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RGS14 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC (p), IF
Validierungen
- (3)
Kat. Nr.
ABIN524067
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN2856368
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF, ICC
Validierungen
- (2)
Kat. Nr.
ABIN6258314
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene RGS14 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6221040
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RGS14 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317937
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1317939
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124814
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RGS14 Produkten
: "Mossy fiber sprouting into the hippocampal region CA2 in patients with temporal lobe epilepsy." in: Hippocampus, Vol. 31, Issue 6, pp. 580-592, (2021) (PubMed).: "Novel connection between newborn granule neurons and the hippocampal CA2 field." in: Experimental neurology, Vol. 263, pp. 285-92, (2014) (PubMed).
: "Postnatal developmental expression of regulator of G protein signaling 14 (RGS14) in the mouse brain." in: The Journal of comparative neurology, Vol. 522, Issue 1, pp. 186-203, (2014) (PubMed).
: "Cell type-specific genetic and optogenetic tools reveal hippocampal CA2 circuits." in: Nature neuroscience, Vol. 17, Issue 2, pp. 269-79, (2014) (PubMed).
: "The hippocampal CA2 region is essential for social memory." in: Nature, Vol. 508, Issue 7494, pp. 88-92, (2014) (PubMed).
: "Assembly and function of the regulator of G protein signaling 14 (RGS14)·H-Ras signaling complex in live cells are regulated by G?i1 and G?i-linked G protein-coupled receptors." in: The Journal of biological chemistry, Vol. 288, Issue 5, pp. 3620-31, (2013) (PubMed).
: "Delta-opioid receptors mediate unique plasticity onto parvalbumin-expressing interneurons in area CA2 of the hippocampus." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 36, pp. 14567-78, (2013) (PubMed).
: "Activation of the regulator of G protein signaling 14-G?i1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8A." in: Biochemistry, Vol. 50, Issue 5, pp. 752-62, (2011) (PubMed).
: "RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 39, pp. 16994-8, (2010) (PubMed).
: "Molecular cloning and expression analysis of rat Rgs12 and Rgs14." in: Biochemical and biophysical research communications, Vol. 233, Issue 3, pp. 770-7, (1997) (PubMed).
Synonyme und alternative Namen zu RGS14
regulator of G protein signaling 14 (RGS14), regulator of G-protein signaling 14 (Rgs14), regulator of G-protein signaling 14 L homeolog (rgs14.L), regulator of G-protein signaling 14 (RGS14), regulator of G-protein signalling 14 (rgs14), regulator of G protein signaling 14 (Rgs14), regulator of G protein signaling 14a (rgs14a), MGC80558, RGS14, rgs14, RPIP1, wu:fi04g12Bezeichner auf Proteinebene für RGS14
- regulator of G-protein signalling 14
- RAP1/RAP2-interacting protein
- rap1/rap2 interacting protein
- regulator of G-protein signaling 14
- Regulator of G-protein signaling 14
- regulator of G-protein signaling 14-like
- LOW QUALITY PROTEIN: regulator of G-protein signaling 14
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