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RGS14 Antikörper (Regulator of G-Protein Signaling 14) (C-Term) Primary Antibody

RGS14 Reaktivität: Human IHC (p), WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2856368
$509.08
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 3 bis 4 Werktagen
  • Target
    RGS14
    Bindungsspezifität
    C-Term
    • 10
    • 9
    • 8
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Reaktivität
    Human
    • 54
    • 18
    • 11
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Wirt
    Kaninchen
    • 43
    • 7
    • 4
    • 1
    Klonalität
    Polyklonal
    • 53
    • 2
    Konjugat
    Dieser RGS14 Antikörper ist unkonjugiert
    • 28
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Applikation
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    • 47
    • 32
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Produktmerkmale
    Rabbit Polyclonal antibody to RGS14 (regulator of G-protein signaling 14)
    RGS14 antibody [C3], C-term
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RGS14. The exact sequence is proprietary.
    Isotyp
    IgG
  • Applikationshinweise
    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    Kommentare

    Positive Control: Jurkat

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.93 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    RGS14
    Andere Bezeichnung
    RGS14 (RGS14 Antibody Abstract)
    Synonyme
    RPIP1, MGC80558, RGS14, rgs14, wu:fi04g12, regulator of G protein signaling 14, regulator of G-protein signaling 14, regulator of G-protein signaling 14 L homeolog, regulator of G-protein signalling 14, regulator of G protein signaling 14a, RGS14, Rgs14, rgs14.L, rgs14, rgs14a
    Hintergrund
    This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

    Cellular Localization: Membrane
    Molekulargewicht
    61 kDa
    Gen-ID
    10636
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
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