ARHGDIB Protein (GST tag)

Produktnummer ABIN1098209

Produktdetails

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ARHGDIB Protein ist gelabelt mit GST tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: Rho GDP-dissociation inhibitor 2, D4, GDIA2, GDID4, Ly-GDI, LYGDI, RAP1GN1, RhoGDI2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/ml (determined by Bradford assay)

Buffer: phosphate-buffered Saline(pH 7.4) containing 10% glycerol

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Andere Bezeichnung: ARHGDIB (ARHGDIB Produkte)

Synonyme: ARHGDIB Protein, zgc:65966 Protein, arhgdib Protein, MGC69067 Protein, gdia2 Protein, rhodgi-2 Protein, rhodgi2 Protein, D4 Protein, GDIA2 Protein, GDID4 Protein, LYGDI Protein, Ly-GDI Protein, RAP1GN1 Protein, RhoGDI2 Protein, Gdid4 Protein, Rho GDP dissociation inhibitor (GDI) gamma Protein, Rho GDP dissociation inhibitor (GDI) beta S homeolog Protein, Rho GDP dissociation inhibitor beta Protein, Rho GDP dissociation inhibitor (GDI) beta Protein, Rho, GDP dissociation inhibitor (GDI) beta Protein, arhgdig Protein, arhgdib.S Protein, ARHGDIB Protein, arhgdib Protein, Arhgdib Protein

Hintergrund: Members of the Rho (or ARH) protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases. Recombinant human ARHGDIB protein, fused to GST-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 49.4 kDa (428aa)

NCBI Accession: NP_001166

Pathways: Caspase Kaskade in der Apoptose