ARHGDIB Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714888

Produktdetails

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ARHGDIB Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ARHGDIB / D4-GDI protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))

Andere Bezeichnung: Arhgdib,d4-Gdi (ARHGDIB Produkte)

Synonyme: ARHGDIB Protein, zgc:65966 Protein, arhgdib Protein, MGC69067 Protein, gdia2 Protein, rhodgi-2 Protein, rhodgi2 Protein, D4 Protein, GDIA2 Protein, GDID4 Protein, LYGDI Protein, Ly-GDI Protein, RAP1GN1 Protein, RhoGDI2 Protein, Gdid4 Protein, Rho GDP dissociation inhibitor (GDI) gamma Protein, Rho GDP dissociation inhibitor (GDI) beta S homeolog Protein, Rho GDP dissociation inhibitor beta Protein, Rho GDP dissociation inhibitor (GDI) beta Protein, Rho, GDP dissociation inhibitor (GDI) beta Protein, arhgdig Protein, arhgdib.S Protein, ARHGDIB Protein, arhgdib Protein, Arhgdib Protein

Hintergrund: Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM, Dec 2010].

Molekulargewicht: 22.8 kDa

NCBI Accession: NP_001166

Pathways: Caspase Kaskade in der Apoptose