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Interferon gamma Protein (IFNG) (AA 24-166) (His tag)

IFNG Spezies: Human Wirt: HEK-293 Cells > 95 % CC, AcA Active
Produktnummer ABIN6239726
  • Target Alle Interferon gamma (IFNG) Proteine anzeigen
    Interferon gamma (IFNG)
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 24-166
    Spezies
    • 26
    • 15
    • 13
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 54
    • 34
    • 13
    • 6
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Interferon gamma Protein ist gelabelt mit His tag.
    Applikation
    Cell Culture (CC), Activity Assay (AcA)
    Produktmerkmale
    Tag location: N-terminal His Tag
    Reinheit
    > 95 %
    Biological Activity Comment
    IFN-γ is a dimerized soluble cytokine that is the only member of the type II class of interferons.The importance of IFNγ in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. As reported, IFNγ is an important activator of human monocytic THP1 cells. Therefore,THP-1 cells were incubated in RPMI 1640 with various concentration of IFN-γ , then cells were observed by inverted microscope everyday.After stimulated with IFN-γ(5ng/ml) for 5 days, morphological changes occured in THP1 cells which displayed the shape of fusiform or polygon and were more likely to adhere. Effect of IFN-γ on THP1 cells is shown in Figure 1.
    Top Product
    Discover our top product IFNG Protein
  • Applikationshinweise
    Isoelectric Point: 9.7
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01 % SKL, 5 % Trehalose and Proclin300.
    Konservierungsmittel
    Dithiothreitol (DTT), Other preservative, ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin and Dithiothreitol (DTT): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
  • Target
    Interferon gamma (IFNG)
    Abstract
    IFNG Produkte
    Synonyme
    IFG Protein, IFI Protein, IFN-g Protein, Ifg Protein, IFNG2 Protein, IFN-gamma Protein, IFN-G Protein, IFNG Protein, IFNgamma Protein, TCRalpha Protein, INF-G Protein, ifng Protein, interferon gamma Protein, interferon, gamma 1-2 Protein, IFNG Protein, Ifng Protein, ifng1-2 Protein
    Hintergrund
    Alternative Names: IFN-G, IFG, IFI, INFr, IFN, Immune Interferon
    Molekulargewicht
    22&25kDa
    UniProt
    P01579
    Pathways
    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie
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