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Epiregulin Protein (EREG)

EREG Spezies: Human Recombinant > 97 % as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Produktnummer ABIN621713
  • Target Alle Epiregulin (EREG) Proteine anzeigen
    Epiregulin (EREG)
    Protein-Typ
    Recombinant
    Spezies
    • 12
    • 4
    • 1
    Human
    Wirt
    Bitte anfragen
    Sequenz
    MVAQVSITKC SSDMNGYCLH GQCIYLVDMS QNYCRCEVGY TGV
    Produktmerkmale
    Recombinant Human Epiregulin
    Reinheit
    > 97 % as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
    Top Product
    Discover our top product EREG Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Epiregulin was lyophilized from 0.5mg/ml solution ciontaing 20mM PBS buffer pH-7.4 containing 130mM sodium chloride.It is recommended to reconstitute the lyophilized Epiregulin in sterile 18M -cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
    Lagerung
    -20 °C
  • Target
    Epiregulin (EREG)
    Andere Bezeichnung
    Epiregulin (EREG Produkte)
    Synonyme
    EREG Protein, ER Protein, EPR Protein, proepiregulin Protein, epiregulin Protein, EREG Protein, ereg Protein, Ereg Protein
    Hintergrund
    Epiregulin Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 50 amino acids and having a molecular mass of 6 kDa. Epiregulin is purified by proprietary chromatographic techniques. Introduction: Epiregulin is part of the EGF family. Epiregulin functions as a ligand of EGFR, as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. Epiregulin is expressed mostly in the placenta and peripheral blood leukocytes and in specific carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. Epiregulin inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence. Synonyms: EREG, Epiregulin, ER.
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation
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