Epiregulin Protein (EREG)
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- Target Alle Epiregulin (EREG) Proteine anzeigen
- Epiregulin (EREG)
- Protein-Typ
- Recombinant
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Spezies
- Human
- Wirt
- Bitte anfragen
- Sequenz
- MVAQVSITKC SSDMNGYCLH GQCIYLVDMS QNYCRCEVGY TGV
- Produktmerkmale
- Recombinant Human Epiregulin
- Reinheit
- > 97 % as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
- Top Product
- Discover our top product EREG Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Epiregulin was lyophilized from 0.5mg/ml solution ciontaing 20mM PBS buffer pH-7.4 containing 130mM sodium chloride.It is recommended to reconstitute the lyophilized Epiregulin in sterile 18M -cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
- Lagerung
- -20 °C
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- Target
- Epiregulin (EREG)
- Andere Bezeichnung
- Epiregulin (EREG Produkte)
- Synonyme
- EREG Protein, ER Protein, EPR Protein, proepiregulin Protein, epiregulin Protein, EREG Protein, ereg Protein, Ereg Protein
- Hintergrund
- Epiregulin Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 50 amino acids and having a molecular mass of 6 kDa. Epiregulin is purified by proprietary chromatographic techniques. Introduction: Epiregulin is part of the EGF family. Epiregulin functions as a ligand of EGFR, as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. Epiregulin is expressed mostly in the placenta and peripheral blood leukocytes and in specific carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and vascular smooth muscle cells. Epiregulin inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence. Synonyms: EREG, Epiregulin, ER.
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation
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