TUBG1 Protein (AA 1-451) (His tag)

Produktnummer ABIN5855121

Produktdetails

Target: TUBG1 (Tubulin, gamma 1 (TUBG1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-451

Spezies: Human

Quelle: Baculovirus infected Insect Cells

Aufreinigungstag / Konjugat: Dieses TUBG1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MPREIITLQL GQCGNQIGFE FWKQLCAEHG ISPEGIVEEF ATEGTDRKDV FFYQADDEHY IPRAVLLDLE PRVIHSILNS PYAKLYNPEN IYLSEHGGGA GNNWASGFSQ GEKIHEDIFD IIDREADGSD SLEGFVLCHS IAGGTGSGLG SYLLERLNDR YPKKLVQTYS VFPNQDEMSD VVVQPYNSLL TLKRLTQNAD CVVVLDNTAL NRIATDRLHI QNPSFSQINQ LVSTIMSAST TTLRYPGYMN NDLIGLIASL IPTPRLHFLM TGYTPLTTDQ SVASVRKTTV LDVMRRLLQP KNVMVSTGRD RQTNHCYIAI LNIIQGEVDP TQVHKSLQRI RERKLANFIP WGPASIQVAL SRKSPYLPSA HRVSGLMMAN HTSISSLFER TCRQYDKLRK REAFLEQFRK EDMFKDNFDE MDTSREIVQQ LIDEYHAATR PDYISWGTQE QHHHHHH

Reinheit: > 85 % by SDS - PAGE

Endotoxin-Niveau: < 1.0 EU per 1ug of protein (determined by LAL method)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl (  pH 8.0) containing 40 % glycerol, 0.1M NaCl, 2  mM DTT, 50  mM imidazole.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: TUBG1 (Tubulin, gamma 1 (TUBG1))

Andere Bezeichnung: TUBG1 (TUBG1 Produkte)

Synonyme: GCP-1 Protein, TUBG Protein, TUBGCP1 Protein, TUBC Protein, TUBG3 Protein, gamma-tubulin Protein, Tubg2 Protein, xgam Protein, 1500010O08Rik Protein, AI451582 Protein, AI503389 Protein, Tubg Protein, tubgl Protein, zgc:55894 Protein, tubulin gamma 1 Protein, gamma-tubulin 1 Protein, gamma-tubulin Protein, tubulin gamma 1 L homeolog Protein, Tubulin gamma chain Protein, tubulin, gamma 1 Protein, tubulin gamma-1 chain Protein, TUBG1 Protein, tubg1 Protein, tubg1.L Protein, tbg-1 Protein, Tubg1 Protein, LOC101686824 Protein, LOC101103906 Protein

Hintergrund: TUBG1, also known as tubulin gamma-1 chain, is a member of the tubulin superfamily. This protein is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. It is the pericentriolar matrix component that regulates alpha/beta tubulin minus-end nucleation, centrosome duplication and spindle formation. It is required for microtubule formation and progression of the cell cycle. Also, this protein is interacts with GCP2, GCP3, and B9D2. The interaction is leading to centrosomal localization of TUBG1 and CDK5RAP2. Recombinant human TUBG1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Molekulargewicht: 51.9kDa (457aa) 50-70kDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_001061

UniProt: P23258

Pathways: Microtubule Dynamics, M Phase