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CNTF Receptor alpha Protein (AA 23-342) (His tag)

CNTFR Spezies: Ratte Wirt: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN5854746
  • Target Alle CNTF Receptor alpha (CNTFR) Proteine anzeigen
    CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 23-342
    Spezies
    • 9
    • 3
    • 1
    • 1
    • 1
    Ratte
    Quelle
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Baculovirus infected Insect Cells
    Aufreinigungstag / Konjugat
    Dieses CNTF Receptor alpha Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    QKHSPQEAPH VQYERLGTDV TLPCGTASWD AAVTWRVNGT DLAPDLLNGS QLILRSLELG HSGLYACFHR DSWHLRHQVL LHVGLPPREP VLSCRSNTYP KGFYCSWHLS APTYIPNTFN VTVLHGSKMM VCEKDPALKN RCHIRYMHLF STIKYKVSIS VSNALGHNTT AITFDEFTIV KPDPPENVVA RPVPSNPRRL EVTWQTPSTW PDPESFPLKF FLRYRPLILD QWQHVELSNG TAHTITDAYA GKEYIIQVAA KDNEIGTWSD WSVAAHATPW TEEPRHLTTE AQAPETTTST TSSLAPPPTT KICDPGELSS LEHHHHHH
    Reinheit
    > 90 % by SDS - PAGE
    Endotoxin-Niveau
    < 1.0 EU per 1 microgram of protein (determined by LAL method)
    Top Product
    Discover our top product CNTFR Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))
    Andere Bezeichnung
    Cntfr (CNTFR Produkte)
    Synonyme
    CNTFR-alpha Protein, CNTFRALPHA Protein, Cntfralpha Protein, cb549 Protein, fj33e02 Protein, sb:cb549 Protein, wu:fj33e02 Protein, si:bz76a6.1 Protein, si:dz248f2.1 Protein, si:rp71-76a6.1 Protein, ciliary neurotrophic factor receptor Protein, ciliary neurotrophic factor receptor L homeolog Protein, CNTFR Protein, cntfr.L Protein, Cntfr Protein, cntfr Protein
    Hintergrund
    Cntfr, also known as ciliary neurotrophic factor receptor subunit alpha, is a member of the type 1 cytokine receptor family. It mediates the biological action of CNTF. CNTF is a polypeptide hormone that supports the survival of neurons of the peripheral sensory, sympathetic, and ciliary ganglia at various stages in their development. CNTFR and its cognate ligand support the survival of neurons. The CNTF receptor complex is most closely related to, and shares subunits with the receptor complexes for interleukin-6 and leukemia inhibitory factor. The specificity conferring alpha subunit of the CNTF complex (CNTFR alpha), is extremely well conserved across species, and has a distribution localized predominantly to the nervous system and skeletal muscle. Recombinant rat Cntfr, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molekulargewicht
    36.9kDa (328aa) 40-57KDa (SDS-PAGE under reducing conditions.)
    NCBI Accession
    NP_001003929
    UniProt
    Q08406
    Pathways
    JAK-STAT Signalweg, Feeding Behaviour
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