LRPAP1 Protein (AA 29-360) (His tag)

Produktnummer ABIN5854296

Produktdetails

Target: LRPAP1 (Low Density Lipoprotein Receptor-Related Protein Associated Protein 1 (LRPAP1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 29-360

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses LRPAP1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSQPIAGHG GKYSREKNEP EMAAKRESGE EFRMEKLNQL WEKAKRLHLS PVRLAELHSD LKIQERDELN WKKLKVEGLD KDGEKEAKLI HNLNVILARY GLDGRKDAQM VHSNALNEDT QDELGDPRLE KLWHKAKTSG KFSSEELDKL WREFLHYKEK IQEYNVLLDT LSRAEEGYEN LLSPSDMAHI KSDTLISKHS ELKDRLRSIN QGLDRLRKVS HQGYGSTTEF EEPRVIDLWD LAQSANFTEK ELESFREELK HFEAKIEKHN HYQKQLEISH QKLKHVESIG DPEHISRNKE KYVLLEEKTK ELGYKVKKHL QDLSSRVSRA RHNEL

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid, In Phosphate buffered saline (  pH 7.4) containing 10 % glycerol

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: LRPAP1 (Low Density Lipoprotein Receptor-Related Protein Associated Protein 1 (LRPAP1))

Andere Bezeichnung: Lrpap1 (LRPAP1 Produkte)

Synonyme: wu:fi20f07 Protein, wu:fi22c06 Protein, LRPAP1 Protein, DKFZp459I2430 Protein, A2MRAP Protein, A2RAP Protein, HBP44 Protein, MRAP Protein, RAP Protein, AA617339 Protein, AI790446 Protein, AU042172 Protein, C77774 Protein, alpha-2-macroglobulin receptor-associated protein-like Protein, low density lipoprotein receptor-related protein associated protein 1 Protein, LDL receptor related protein associated protein 1 Protein, LDL receptor related protein associated protein 1 L homeolog Protein, LOC100231803 Protein, lrpap1 Protein, LRPAP1 Protein, Lrpap1 Protein, lrpap1.L Protein

Hintergrund: Lrpap1 also known as Alpha-2-macroglobulin receptor-associated protein. The alpha-2-macroglobulin receptor-associated protein (RAP) is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. Lrpap1 acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. Lrpap1 may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II. Recombinant mouse Lspap1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 41.4kDa (355aa) confirmed by MALDI-TOF

NCBI Accession: NP_038615

UniProt: P55302