SFRP5 Protein (AA 30-317) (His tag)

Produktnummer ABIN5854078

Produktdetails

Target: SFRP5 (Secreted Frizzled-Related Protein 5 (SFRP5))

Protein-Typ: Recombinant

Proteineigenschaft: AA 30-317

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SFRP5 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSEEYDYYG WQAEPLHGRS YSKPPQCLDI PADLPLCHTV GYKRMRLPNL LEHESLAEVK QQASSWLPLL AKRCHSDTQV FLCSLFAPVC LDRPIYPCRS LCEAVRAGCA PLMEAYGFPW PEMLHCHKFP LDNDLCIAVQ FGHLPATAPP VTKICAQCEM EHSADGLMEQ MCSSDFVVKM RIKEIKIENG DRKLIGAQKK KKLLKPGPLK RKDTKRLVLH MKNGAGCPCP QLDSLAGSFL VMGRKVDGQL LLMAVYRWDK KNKEMKFAVK FMFSYPCSLY YPFFYGAAEP H

Reinheit: > 85 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Denatured

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl(  pH 8.0) containing 10 % glycerol.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: SFRP5 (Secreted Frizzled-Related Protein 5 (SFRP5))

Andere Bezeichnung: SFRP5 (SFRP5 Produkte)

Synonyme: SARP3 Protein, AI605071 Protein, D144 Protein, frp1 Protein, zgc:101849 Protein, Sfrp5 Protein, XsFRP5 Protein, frp5 Protein, sFRP-5 Protein, sarp3 Protein, sfrp5 Protein, sfrp5-a Protein, sfrp5-b Protein, secreted frizzled related protein 5 Protein, secreted frizzled-related sequence protein 5 Protein, secreted frizzled-related protein 5 Protein, secreted frizzled-related protein 5 L homeolog Protein, secreted frizzled-related protein 5 S homeolog Protein, SFRP5 Protein, Sfrp5 Protein, sfrp5 Protein, sfrp5.L Protein, sfrp5.S Protein

Hintergrund: SARP3, also known as secreted frizzled-related protein 5, is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas. Recombinant SFRP5, fused to His-tag at N-terminus, was expressed in E.coli.

Molekulargewicht: 35kDa (311aa)

NCBI Accession: NP_003006

UniProt: Q5T4F7

Pathways: WNT Signalweg