UNG Protein (AA 1-229) (His tag)

Produktnummer ABIN5853288

Produktdetails

Target: UNG (Uracil-DNA Glycosylase (UNG))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-229

Spezies: E. coli

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses UNG Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMANELTW HDVLAEEKQQ PYFLNTLQTV ASERQSGVTI YPPQKDVFNA FRFTELGDVK VVILGQDPYH GPGQAHGLAF SVRPGIAIPP SLLNMYKELE NTIPGFTRPN HGYLESWARQ GVLLLNTVLT VRAGQAHSHA SLGWETFTDK VISLINQHRE GVVFLLWGSH AQKKGAIIDK QRHHVLKAPH PSPLSAHRGF FGCNHFVLAN QWLEQRGETP IDWMPVLPAE SE

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: UNG (Uracil-DNA Glycosylase (UNG))

Andere Bezeichnung: ung (UNG Produkte)

Synonyme: DGU Protein, HIGM4 Protein, HIGM5 Protein, UDG Protein, UNG1 Protein, UNG15 Protein, UNG2 Protein, ung Protein, zgc:56102 Protein, PSPTO4236 Protein, BA5648 Protein, ECK2578 Protein, JW2564 Protein, An02g14790 Protein, AO090001000732 Protein, DDBDRAFT_0204444 Protein, DDBDRAFT_0214910 Protein, DDB_0204444 Protein, DDB_0214910 Protein, uracil-DNA glycosylase Protein, uracil DNA glycosylase Protein, uracil DNA glycosylase a Protein, uracil-DNA glycosylase Ung Protein, uracil-DNA-glycosylase Protein, uracil DNA glycosylase L homeolog Protein, uracil glycosylase Protein, temporal expression: early Protein, ung Protein, ung2 Protein, Ung Protein, UNG Protein, unga Protein, STY2840 Protein, ung.L Protein, ANI_1_3358024 Protein, AOR_1_1318164 Protein, uglA Protein, Arnit_2731 Protein, D4R Protein

Substanzklasse: Viral Protein

Hintergrund: Ung, also known as uracil-DNA glycosylase, is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. uracil bases occur from cytosine deamination or misincorporation of duMP residues. After a mutation occurs, the mutagenic threat of uracil propagates through any subsequent DNA replication steps. Recombinant E.coli ung protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Molekulargewicht: 28.1 kDa(252aa) confirmed by MALDI-TOF

NCBI Accession: NP_417075

UniProt: P12295

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response