COPS6 Protein (AA 1-327) (His tag)

Produktnummer ABIN5853156

Produktdetails

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-327

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses COPS6 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MAAAAAAAAA TNGTGGSSGM EVDAAVVPSV MACGVTGSVS VALHPLVILN ISDHWIRMRS QEGRPVQVIG ALIGKQEGRN IEVMNSFELL SHTVEEKIII DKEYYYTKEE QFKQVFKELE FLGWYTTGGP PDPSDIHVHK QVCEIIESPL FLKLNPMTKH TDLPVSVFES VIDIINGEAT MLFAELTYTL ATEEAERIGV DHVARMTATG SGENSTVAEH LIAQHSAIKM LHSRVKLILE YVKASEAGEV PFNHEILREA YALCHCLPVL STDKFKTDFY DQCNDVGLMA YLGTITKTCN TMNQFVNKFN VLYDRQGIGR RMRGLFF

Reinheit: > 80 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Denatured

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M uREA, 10 % glycerol

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))

Andere Bezeichnung: COPS6 (COPS6 Produkte)

Synonyme: CG6932 Protein, CH6 Protein, Csn6 Protein, Dch6 Protein, Dmel\\CG6932 Protein, zgc:112075 Protein, Sgn3 Protein, VIP/MOV34 Protein, CSN6 Protein, MOV34-34KD Protein, COP9 signalosome subunit 6 Protein, COP-9 SigNalosome subunit Protein, COPS6 Protein, Cops6 Protein, CSN6 Protein, cops6 Protein, csn-6 Protein

Hintergrund: COPS6 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. Recombinant human COPS6 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molekulargewicht: 38.9kDa (347aa)

NCBI Accession: NP_006824

UniProt: Q7L5N1

Pathways: Zellzyklus