POLE3 Protein (AA 1-147) (His tag)

Produktnummer ABIN5853016

Produktdetails

Target: POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-147

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses POLE3 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MGSSHHHHHH SSGLVPRGSH MGSMAERPED LNLPNAVITR IIKEALPDGV NISKEARSAI SRAASVFVLY ATSCANNFAM KGKRKTLNAS DVLSAMEEME FQRFVTPLKE ALEAYRREQK GKKEASEQKK KDKDKKTDSE EQDKSRDEDN DEDEERLEEE EQNEEEEVDN

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.2M NaCl, 20 % glycerol, 1  mM DTT.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: POLE3 (Polymerase (DNA Directed), epsilon 3 (p17 Subunit) (POLE3))

Andere Bezeichnung: POLE3 (POLE3 Produkte)

Synonyme: NCU04548.1 Protein, GB14966 Protein, zgc:73351 Protein, 1810034K18Rik Protein, YBL1 Protein, CHARAC17 Protein, CHRAC17 Protein, p17 Protein, DNA polymerase epsilon 3, accessory subunit Protein, polymerase (DNA directed), epsilon 3, accessory subunit Protein, DNA polymerase epsilon Protein, DNA polymerase epsilon p17 subunit Protein, DNA polymerase epsilon subunit 3 Protein, polymerase (DNA directed), epsilon 3 (p17 subunit) Protein, POLE3 Protein, pole3 Protein, NCU04548 Protein, CpipJ_CPIJ008666 Protein, Bm1_04865 Protein, Bm1_07285 Protein, CTRG_00708 Protein, LOAG_09571 Protein, LOC726923 Protein, Pole3 Protein

Hintergrund: POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging. POLE3 has been shown to interact with SMARCA5. Recombinant human POLE3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 19kDa (170aa), confirmed by MALDI-TOF

NCBI Accession: NP_059139

UniProt: Q9NRF9

Pathways: DNA Reparatur