DIO3 Protein (AA 37-278, Extracellular) (His tag)
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- Target Alle DIO3 Proteine anzeigen
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Extracellular, AA 37-278
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Spezies
- Ratte
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Quelle
- Hefe
- Aufreinigungstag / Konjugat
- Dieses DIO3 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- DFLCIRKHFL RRRHPDHPEP EVELNSEGEE MPPDDPPICV SDDNRLCTLA SLKAVWHGQK LDFFKQAHEG GPAPNSEVVR PDGFQSQRIL DYAQGTRPLV LNFGSCTPPF MARMSAFQRL VTKYQRDVDF LIIYIEEAHP SDGWVTTDSP YVIPQHRSLE DRVSAARVLQ QGAPGCALVL DTMANSSSSA YGAYFERLYV IQSGTIMYQG GRGPDGYQVS ELRTWLERYD EQLHGTRPRR L
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product DIO3 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
- Andere Bezeichnung
- IOD3 (DIO3 Produkte)
- Synonyme
- 5DIII Protein, DIOIII Protein, txdi3 Protein, dioiii Protein, XL-15 Protein, itdi3 Protein, D3 Protein, TXDI3 Protein, iodothyronine deiodinase 3 Protein, deiodinase, iodothyronine, type 3 Protein, deiodinase, iodothyronine, type III Protein, deiodinase, iodothyronine type III Protein, deiodinase, iodothyronine, type 3 L homeolog Protein, DIO3 Protein, dio3 Protein, Dio3 Protein, dio3.L Protein
- Hintergrund
- Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing prature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during bryological development.
- Molekulargewicht
- 29.4 kDa
- UniProt
- P49897
- Pathways
- Hormone Activity
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