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DIO3 Protein (AA 37-278, Extracellular) (His tag)

DIO3 Spezies: Ratte Wirt: Hefe Recombinant > 90 % SDS
Produktnummer ABIN5714130
  • Target Alle DIO3 Proteine anzeigen
    DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Extracellular, AA 37-278
    Spezies
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte
    Quelle
    • 7
    • 6
    • 2
    • 2
    Hefe
    Aufreinigungstag / Konjugat
    Dieses DIO3 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    DFLCIRKHFL RRRHPDHPEP EVELNSEGEE MPPDDPPICV SDDNRLCTLA SLKAVWHGQK LDFFKQAHEG GPAPNSEVVR PDGFQSQRIL DYAQGTRPLV LNFGSCTPPF MARMSAFQRL VTKYQRDVDF LIIYIEEAHP SDGWVTTDSP YVIPQHRSLE DRVSAARVLQ QGAPGCALVL DTMANSSSSA YGAYFERLYV IQSGTIMYQG GRGPDGYQVS ELRTWLERYD EQLHGTRPRR L
    Aufreinigung
    SDS-PAGE
    Reinheit
    > 90 %
    Top Product
    Discover our top product DIO3 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Lagerung
    -80 °C,4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    DIO3 (Deiodinase, Iodothyronine, Type III (DIO3))
    Andere Bezeichnung
    IOD3 (DIO3 Produkte)
    Synonyme
    5DIII Protein, DIOIII Protein, txdi3 Protein, dioiii Protein, XL-15 Protein, itdi3 Protein, D3 Protein, TXDI3 Protein, iodothyronine deiodinase 3 Protein, deiodinase, iodothyronine, type 3 Protein, deiodinase, iodothyronine, type III Protein, deiodinase, iodothyronine type III Protein, deiodinase, iodothyronine, type 3 L homeolog Protein, DIO3 Protein, dio3 Protein, Dio3 Protein, dio3.L Protein
    Hintergrund
    Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing prature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during bryological development.
    Molekulargewicht
    29.4 kDa
    UniProt
    P49897
    Pathways
    Hormone Activity
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