MIB1 Protein (AA 5-332, partial) (His tag)
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- Target Alle MIB1 Proteine anzeigen
- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 5-332, partial
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses MIB1 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- RNNRVMVEGV GARVVRGPDW KWGKQDGGEG HVGTVRSFES PEEVVVVWDN GTAANYRCSG AYDLRILDSA PTGIKHDGTM CDTCRQQPII GIRWKCAECT NYDLCTVCYH GDKHHLRHRF YRITTPGSER VLLESRRKSK KITARGIFAG ARVVRGVDWQ WEDQDGGNGR RGKVTEIQDW SASSPHSAAY VLWDNGAKNL YRVGFEGMSD LKCVQDAKGG SFYRDHCPVL GEQNGNRNPG GLQIGDLVNI DLDLEIVQSL QHGHGGWTDG MFETLTTTGT VCGIDEDHDI VVQYPSGNRW TFNPAVLTKA NIVRSGDAAQ GAEGGTSQ
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product MIB1 Protein
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Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 909-1006) protein (GST tag)
MIB1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 1-1006) protein (Strep Tag)Crystallography grade MIB1 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 1-1006) protein (Strep Tag)Crystallography grade MIB1 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) protein (Myc-DYKDDDDK Tag)MIB1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 5-332), (partial) protein (His tag)MIB1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 90 % ELISA
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
- Andere Bezeichnung
- MIB1 (MIB1 Produkte)
- Synonyme
- DIP-1 Protein, DIP1 Protein, LVNC7 Protein, MIB Protein, ZZANK2 Protein, ZZZ6 Protein, E430019M12Rik Protein, Mib Protein, mKIAA1323 Protein, dip-1 Protein, mib Protein, mindbomb Protein, cg5841 Protein, chunp6889 Protein, fe47f05 Protein, im:7148100 Protein, mib1 Protein, wu:fe47f05 Protein, CG5841 Protein, D-mib Protein, D-mib1 Protein, Dmel\CG5841 Protein, Dmib Protein, MIB1 Protein, Mib1 Protein, dmib1 Protein, l(3)72CDa Protein, l(3)72Db Protein, mib1/2 Protein, mind-bomb Protein, mindbomb E3 ubiquitin protein ligase 1 Protein, mindbomb E3 ubiquitin protein ligase 1 L homeolog Protein, mind bomb 1 Protein, MIB1 Protein, Mib1 Protein, mib1.L Protein, mib1 Protein
- Hintergrund
- E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis . Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits primary cilium formation in proliferating cells. Mediates 'Lys-63'-linked polyubiquitination of TBK1, which probably participates in kinase activation.1 Publication
- Molekulargewicht
- 40.2 kDa
- UniProt
- Q86YT6
- Pathways
- SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
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