MIB1 Protein (Myc-DYKDDDDK Tag)
(1 reference)-
- Target Alle MIB1 Proteine anzeigen
- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses MIB1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human MIB1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MIB1 Protein
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Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 909-1006) protein (GST tag)
MIB1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 1-1006) protein (Strep Tag)Crystallography grade MIB1 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 1-1006) protein (Strep Tag)Crystallography grade MIB1 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 5-332), (partial) protein (His tag)MIB1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 90 % ELISA
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein." in: Molecular biology of the cell, Vol. 24, Issue 12, pp. 1863-71, (2013) (PubMed).
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: "The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein." in: Molecular biology of the cell, Vol. 24, Issue 12, pp. 1863-71, (2013) (PubMed).
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- Target
- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
- Andere Bezeichnung
- Mib1 (MIB1 Produkte)
- Synonyme
- DIP-1 Protein, DIP1 Protein, LVNC7 Protein, MIB Protein, ZZANK2 Protein, ZZZ6 Protein, E430019M12Rik Protein, Mib Protein, mKIAA1323 Protein, dip-1 Protein, mib Protein, mindbomb Protein, cg5841 Protein, chunp6889 Protein, fe47f05 Protein, im:7148100 Protein, mib1 Protein, wu:fe47f05 Protein, CG5841 Protein, D-mib Protein, D-mib1 Protein, Dmel\CG5841 Protein, Dmib Protein, MIB1 Protein, Mib1 Protein, dmib1 Protein, l(3)72CDa Protein, l(3)72Db Protein, mib1/2 Protein, mind-bomb Protein, mindbomb E3 ubiquitin protein ligase 1 Protein, mindbomb E3 ubiquitin protein ligase 1 L homeolog Protein, mind bomb 1 Protein, MIB1 Protein, Mib1 Protein, mib1.L Protein, mib1 Protein
- Hintergrund
- This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
- Molekulargewicht
- 110 kDa
- NCBI Accession
- NP_065825
- Pathways
- SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
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