GRP94 Protein (AA 27-799, partial) (His tag)

Produktnummer ABIN5712762

Produktdetails

Target: GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 27-799, partial

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses GRP94 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: VDGTVEEDLG KSREGSRTDD EVVQREEEAI QLDGLNASQI RELREKSEKF AFQAEVNRMM KLIINSLYKN KEIFLRELIS NASDALDKIR LISLTDENAL SGNEELTVKI KCDKEKNLLH VTDTGVGMTR EELVKNLGTI AKSGTSEFLN KMTEAQEDGQ STSELIGQFG VGFYSAFLVA DKVIVTSKHN NDTQHIWESD SNEFSVIADP RGNTLGRGTT ITLVLKEEAS DYLELDTIKN LVKKYSQFIN FPIYVWSSKT ETVEEPMEEE EAAKEEKEES DDEAAVEEEE EEKKPKTKKV EKTVWDWELM NDIKPIWQRP SKEVEEDEYK AFYKSFSKES DDPMAYIHFT AEGEVTFKSI LFVPTSAPRG LFDEYGSKKS DYIKLYVRRV FITDDFHDMM PKYLNFVKGV VDSDDLPLNV SRETLQQHKL LKVIRKKLVR KTLDMIKKIA DDKYNDTFWK EFGTNIKLGV IEDHSNRTRL AKLLRFQSSH HPTDITSLDQ YVERMKEKQD KIYFMAGSSR KEAESSPFVE RLLKKGYEVI YLTEPVDEYC IQALPEFDGK RFQNVAKEGV KFDESEKTKE SREAVEKEFE PLLNWMKDKA LKDKIEKAVV SQRLTESPCA LVASQYGWSG NMERIMKAQA YQTGKDISTN YYASQKKTFE INPRHPLIRD MLRRIKEDED DKTVLDLAVV LFETATLRSG YLLPDTKAYG DRIERMLRLS LNIDPDAKVE EEPEEEPEET AEDTTEDTEQ DEDEEMDVGT DEEEETAKES TAE

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))

Andere Bezeichnung: ENPL (HSP90B1 Produkte)

Synonyme: ecgp Protein, gp96 Protein, tra1 Protein, grp94 Protein, DDBDRAFT_0206450 Protein, DDBDRAFT_0215015 Protein, DDB_0206450 Protein, DDB_0215015 Protein, TRA1 Protein, HSP90B1 Protein, ERp99 Protein, GRP94 Protein, TA-3 Protein, Targ2 Protein, Tra-1 Protein, Tra1 Protein, endoplasmin Protein, GP96 Protein, fb61d09 Protein, tra-1 Protein, wu:fb61d09 Protein, wu:fq25g01 Protein, Grp94 Protein, ECGP Protein, Gp96 Protein, ppk98 Protein, hsp108 Protein, heat shock protein 90kDa beta (Grp94), member 1 Protein, heat shock protein Hsp90 family protein Protein, 94 kD glucose-regulated protein Protein, heat shock protein 90 beta family member 1 Protein, heat shock protein 90, beta (Grp94), member 1 Protein, heat shock protein 90, beta (grp94), member 1 Protein, heat shock protein 90kDa beta family member 1 L homeolog Protein, hsp90b1 Protein, grp94 Protein, HSP90B1 Protein, Hsp90b1 Protein, hsp90b1.L Protein

Hintergrund: Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors . Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.1 Publication

Molekulargewicht: 93.2 kDa

UniProt: P14625

Pathways: Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades