ILK Protein (AA 1-228, partial) (His tag)

Produktnummer ABIN5712103

Produktdetails

Target: ILK (Integrin-Linked Kinase (ILK))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-228, partial

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ILK Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW ACREGRSAVV EMLIMRGARI NVMNRGDDTP LHLAASHGHR DIVQKLLQYK ADINAVNEHG NVPLHYACFW GQDQVAEDLV ANGALVSICN KYGEMPVDKA KAPLRELLRE RAEKMGQNLN RIPYKDTFWK GTTRTRPRNG TLNKHSGIDF KQLNFLTKLN ENHSGELWKG RWQGNDIVVK VLKVRDWS

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: ILK (Integrin-Linked Kinase (ILK))

Andere Bezeichnung: ILK (ILK Produkte)

Synonyme: CG10504 Protein, CT29478 Protein, DmILK Protein, Dmel\\CG10504 Protein, ILK Protein, ilk Protein, l(3)78Ca Protein, p59 Protein, AA511515 Protein, ESTM24 Protein, zgc:65842 Protein, ILK-1 Protein, ILK-2 Protein, P59 Protein, p59ILK Protein, Integrin linked kinase Protein, integrin linked kinase Protein, integrin linked kinase S homeolog Protein, integrin-linked protein kinase Protein, integrin-linked kinase Protein, Ilk Protein, ILK Protein, ilk.S Protein, CpipJ_CPIJ016644 Protein, Bm1_20815 Protein, Tsp_07213 Protein, Tsp_07224 Protein, Tsp_15354 Protein, ilk Protein

Hintergrund: Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.

Molekulargewicht: 30.1 kDa

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration