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ILK Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

ILK Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2723535
  • Target Alle ILK Proteine anzeigen
    ILK (Integrin-Linked Kinase (ILK))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 2
    Spezies
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Quelle
    • 4
    • 3
    • 2
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses ILK Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human Integrin-linked protein kinase (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ILK Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Radovanac, Morgner, Schulz, Blumbach, Patterson, Geiger, Mann, Krieg, Eckes, Fässler, Wickström: "Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response." in: The EMBO journal, Vol. 32, Issue 10, pp. 1409-24, (2013) (PubMed).

  • Target
    ILK (Integrin-Linked Kinase (ILK))
    Andere Bezeichnung
    Integrin-Linked Protein Kinase (ILK Produkte)
    Synonyme
    CG10504 Protein, CT29478 Protein, DmILK Protein, Dmel\\CG10504 Protein, ILK Protein, ilk Protein, l(3)78Ca Protein, p59 Protein, AA511515 Protein, ESTM24 Protein, zgc:65842 Protein, ILK-1 Protein, ILK-2 Protein, P59 Protein, p59ILK Protein, Integrin linked kinase Protein, integrin linked kinase Protein, integrin linked kinase S homeolog Protein, integrin-linked protein kinase Protein, integrin-linked kinase Protein, Ilk Protein, ILK Protein, ilk.S Protein, CpipJ_CPIJ016644 Protein, Bm1_20815 Protein, Tsp_07213 Protein, Tsp_07224 Protein, Tsp_15354 Protein, ilk Protein
    Hintergrund
    This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.
    Molekulargewicht
    51.2 kDa
    NCBI Accession
    NP_001014794
    Pathways
    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
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