Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.1-2 mg/mL
Buffer
20 mM Tris-HCl based buffer, pH 8.0
Lagerung
-80 °C,4 °C,-20 °C
Informationen zur Lagerung
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Target
SNRPA1 (SNRPA)
(Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))
Mud1 Protein, U1-A Protein, U1A Protein, im:7142962 Protein, zgc:101832 Protein, C430021M15Rik Protein, Rnu1a-1 Protein, Rnu1a1 Protein, mud1 Protein, snf Protein, fc19d01 Protein, wu:fc19d01 Protein, zgc:77810 Protein, T30B22.12 Protein, U1SNRNP-SPECIFIC PROTEIN Protein, spliceosomal protein U1A Protein, small nuclear ribonucleoprotein polypeptide A Protein, small nuclear ribonucleoprotein polypeptide A' Protein, small nuclear ribonucleoprotein polypeptide A S homeolog Protein, spliceosomal protein U1A Protein, SNRPA Protein, snrpa1 Protein, Snrpa Protein, snrpa.S Protein, snrpa Protein, U1A Protein
Hintergrund
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assbly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds st loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs.