SNRPA1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2734735

Produktdetails

Target: SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SNRPA1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)

Spezifität: Optimal preservation of protein structure, post-translational modifications and functions.

Produktmerkmale:

• Recombinant human U1 snRNP protein A protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Biological Activity Comment: : OriGene human recombinant small nuclear ribonucleoprotein polypeptide A (SNRPA) was compared side-by-side with baculovirus based insect cell (BEVS) derived SNRPA in a phycoerythrin detecting Luminex assay. The human cell produced SNRPA is comparative or better in sensitivity than the insect cell produced SNRPA to detect autoantibodies in human serum samples.

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: > 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))

Andere Bezeichnung: u1 Snrnp Protein A (SNRPA Produkte)

Synonyme: Mud1 Protein, U1-A Protein, U1A Protein, im:7142962 Protein, zgc:101832 Protein, C430021M15Rik Protein, Rnu1a-1 Protein, Rnu1a1 Protein, mud1 Protein, snf Protein, fc19d01 Protein, wu:fc19d01 Protein, zgc:77810 Protein, T30B22.12 Protein, U1SNRNP-SPECIFIC PROTEIN Protein, spliceosomal protein U1A Protein, small nuclear ribonucleoprotein polypeptide A Protein, small nuclear ribonucleoprotein polypeptide A' Protein, small nuclear ribonucleoprotein polypeptide A S homeolog Protein, spliceosomal protein U1A Protein, SNRPA Protein, snrpa1 Protein, Snrpa Protein, snrpa.S Protein, snrpa Protein, U1A Protein

Hintergrund: The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5&apos splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.

Molekulargewicht: 31.1 kDa

NCBI Accession: NP_004587