ALKBH3 Protein (AA 1-170) (His-SUMO Tag)
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- Target Alle ALKBH3 Proteine anzeigen
- ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-170
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses ALKBH3 Protein ist gelabelt mit His-SUMO Tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MEEKRRRARV QGAWAAPVKS QAIAQPATTA KSHLHQKPGQ TWKNKEHHLS DREFVFKEPQ QVVRRAPEPR VIEEGVYEIS LSPTGVSRVC LYPGFVDVKE ADWILEQLCQ DVPWKQRTGI REDSILQLTF KKSAPVSGTA TAPQSCWYER PSPPHIPGPA ILTRTRLWAP
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product ALKBH3 Protein
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AlkB, Alkylation Repair Homolog 3 (ALKBH3) (AA 1-286) protein (His tag)
ALKBH3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
AlkB, Alkylation Repair Homolog 3 (ALKBH3) (AA 1-139) protein (GST tag)ALKBH3 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AA, AP
AlkB, Alkylation Repair Homolog 3 (ALKBH3) (AA 1-286) protein (Strep Tag)Crystallography grade ALKBH3 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
AlkB, Alkylation Repair Homolog 3 (ALKBH3) (AA 1-286) protein (Strep Tag)Crystallography grade ALKBH3 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
AlkB, Alkylation Repair Homolog 3 (ALKBH3) protein (Myc-DYKDDDDK Tag)ALKBH3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))
- Andere Bezeichnung
- ALKB3 (ALKBH3 Produkte)
- Synonyme
- ABH3 Protein, DEPC-1 Protein, DEPC1 Protein, PCA1 Protein, 1700108H04Rik Protein, 1810020C19Rik Protein, Abh3 Protein, mABH3 Protein, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase L homeolog Protein, alkB homolog 3, alpha-ketoglutaratedependent dioxygenase Protein, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase Protein, alkbh3.L Protein, ALKBH3 Protein, Alkbh3 Protein
- Hintergrund
- Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative dethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.
- Molekulargewicht
- 35.3 kDa
- UniProt
- Q96Q83
- Pathways
- DNA Reparatur
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