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NMNAT3 Protein (AA 1-215, Isoform 2) (His-SUMO Tag)

NMNAT3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Produktnummer ABIN5711591
  • Target Alle NMNAT3 Proteine anzeigen
    NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-215, Isoform 2
    Spezies
    • 4
    • 1
    Human
    Quelle
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses NMNAT3 Protein ist gelabelt mit His-SUMO Tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    MYQVIQGIIS PVNDTYGKKD LAASHHRVAM ARLALQTSDW IRVDPWESEQ AQWMETVKVL RHHHSKLLRS PPQMEGPDHG KALFSTPAAV PELKLLCGAD VLKTFQTPNL WKDAHIQEIV EKFGLVCVGR VGHDPKGYIA ESPILRMHQH NIHLAKEPVQ NEISATYIRR ALGQGQSVKY LIPDAVITYI KDHGLYTKGS TWKGKSTQST EGKTS
    Aufreinigung
    SDS-PAGE
    Reinheit
    > 90 %
    Top Product
    Discover our top product NMNAT3 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Lagerung
    -80 °C,4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    NMNAT3 (Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3))
    Andere Bezeichnung
    NMNA3 (NMNAT3 Produkte)
    Synonyme
    PNAT-3 Protein, PNAT3 Protein, 4933408N02Rik Protein, nicotinamide nucleotide adenylyltransferase 3 Protein, si:ch73-170l17.1 Protein, Nmnat3 Protein, NMNAT3 Protein, si:ch73-170l17.1 Protein
    Hintergrund
    Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, can use NAD+, NADH, NaAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NaADP+. Protects against axonal degeneration following injury.
    Molekulargewicht
    40.1 kDa
    UniProt
    Q96T66
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