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NPHP1 Protein (AA 1-109, partial) (GST tag)

NPHP1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Produktnummer ABIN5710019
  • Target Alle NPHP1 Proteine anzeigen
    NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-109, partial
    Spezies
    • 3
    • 1
    Human
    Quelle
    • 2
    • 2
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses NPHP1 Protein ist gelabelt mit GST tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    MLARRQRDPL QALRRRNQEL KQQVDSLLSE SQLKEALEPN KRQHIYQRCI QLKQAIDENK NALQKLSKAD ESAPVANYNQ RKEEEHTLLD KLTQQLQGLA VTISRENITE
    Aufreinigung
    SDS-PAGE
    Reinheit
    > 90 %
    Top Product
    Discover our top product NPHP1 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Lagerung
    -80 °C,4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    NPHP1 (Nephronophthisis 1 (Juvenile) (NPHP1))
    Andere Bezeichnung
    NPHP1 (NPHP1 Produkte)
    Synonyme
    JBTS4 Protein, NPH1 Protein, SLSN1 Protein, nephrocystin-1 Protein, NPHP1 Protein, im:7162391 Protein, wu:fi59g07 Protein, zgc:152930 Protein, Nphp1 Protein, nephrocystin 1 Protein, nephronophthisis 1 (juvenile) homolog (human) Protein, nephronophthisis 1 (juvenile) L homeolog Protein, nephronophthisis 1 Protein, nephrocystin-1 Protein, NPHP1 Protein, Nphp1 Protein, nphp1.L Protein, nphp1 Protein, LOC100725987 Protein
    Hintergrund
    Together with BCAR1 it may play a role in the control of epithelial cell polarity. Involved in the organization of apical junctions in kidney cells together with NPHP4 and RPGRIP1L/NPHP8 . Does not se to be strictly required for ciliogenesis . Ses to help to recruit PTK2B/PYK2 to cell matrix adhesions, thereby initiating phosphorylation of PTK2B/PYK2 and PTK2B/PYK2-dependent signaling. May play a role in the regulation of intraflagellar transport (IFT) during cilia assbly. Required for normal retina development. In connecting photoreceptor cilia influences the movent of some IFT proteins such as IFT88 and WDR19. Involved in spermatogenesis .
    Molekulargewicht
    40.3 kDa
    UniProt
    O15259
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