Glycoprotein / GP (Virus) (partial) protein (Fc Tag)

Produktnummer ABIN5608207

Produktdetails

Target: Glycoprotein / GP (Virus)

Protein-Typ: Recombinant

Proteineigenschaft: partial

Spezies: Human Herpesvirus 5 (HHV-5)

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Fc Tag

Applikation: Western Blotting (WB)

Sequenz: Val 23 - Lys 700

Reinheit: >85 % as determined by SDS-PAGE.

Endotoxin-Niveau: Endotoxin level is less than 1.0 EU per ug by the LAL method.

Anwendungsinformationen

Applikationshinweise: This recombinant protein can be used for WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, pH 7.5

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.

Antigendetails

Target: Glycoprotein / GP (Virus)

Substanzklasse: Viral Protein

Hintergrund: Human cytomegalovirus is a species of the Cytomegalovirus genus of viruses, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. CMV Virus Envelope Glycoportein B (CMV-GB) can be cleaved into glycoprotein GP55. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. CMV-GB may be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Furthermore, CMV-GB can interact with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also, CMV-GB participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.

Molekulargewicht: 104 kDa

Gen-ID: 223014

UniProt: P13201