IGFBP6 Protein
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- Target Alle IGFBP6 Proteine anzeigen
- IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Hi-5 Cells
- Applikation
- Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)
- Spezifität
- Optimal preservation of protein structure, post-translational modifications and functions.
- Produktmerkmale
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- Recombinant human IGFBP6 protein expressed in Hi-5 insect cells.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Reinheit
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin-Niveau
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by its ability to inhibit IGF-II induced proliferation of human MCF-7 cells. The expected ED50 for this effect is 0.1 - 0.4ug/mL.
- Top Product
- Discover our top product IGFBP6 Protein
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Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) protein (His tag)
IGFBP6 Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) (AA 28-240) protein (His tag)IGFBP6 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) (AA 1-240) protein (GST tag)IGFBP6 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) (Active) protein (His tag)IGFBP6 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE Active
Insulin-Like Growth Factor Binding Protein 6 (IGFBP6) protein (His tag)IGFBP6 Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handhabung
- Resuspend the protein in the desired concentration in proper buffer
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))
- Andere Bezeichnung
- IGFBP6 (IGFBP6 Produkte)
- Synonyme
- IBP6 Protein, IGFBP-6 Protein, IGF-BP6 Protein, RBP6A Protein, IGFBP6 Protein, igfbp6 Protein, insulin like growth factor binding protein 6 Protein, insulin-like growth factor binding protein 6 Protein, IGFBP6 Protein, Igfbp6 Protein, IGFBP-6 Protein, igfbp6 Protein
- Hintergrund
- IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. [UniProtKB/Swiss-Prot Function]
- Molekulargewicht
- 22.6 kDa
- NCBI Accession
- NP_002169
- Pathways
- WNT Signalweg, Myometrial Relaxation and Contraction
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