PCSK9 Protein (AA 1-678) (GST tag)

Produktnummer ABIN3013383

Produktdetails

Target: PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-678

Spezies: Human

Quelle: Wheat germ

Aufreinigungstag / Konjugat: Dieses PCSK9 Protein ist gelabelt mit GST tag.

Applikation: Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Verwendungszweck: PCSK9 (Human) Recombinant Protein (P01)

Sequenz: MGTVSSRRSW WPLPLLLLLL LLLLGPAGAR AQEDEDGLVE APEPGTTATF HRCAKDPWRL PGTYVVVLKE ETHLSQSERT ARRLQAQAAR RGYLTKILHV FHGLLPGFLV KMSGDLLELA LKLPHVDYIE EDSSVFAQSI PWNLERITPP RYRADEYQPP DGGSLVEVYL LDTSIQSDHR EIEGRVMVTD FENVPEEDGT RFHRQASKCD SHGTHLAGVV SGRDAGVAKG ASMRSLRVLN CQGKGTVSGT LIGLEFIRKS QLVQPVGPLV VLLPLAGGYS RVLNAACQRL ARAGVVLVTA AGNFRDDACL YSPAPAPEVI TVGATNAQDQ PVTLGTLGTN FGRCVDLFAP GEDIIGASSD CSTCFVSQSG TSQAAAHVAG IAAMMLSAEP ELTLAELRQR LIHFSAKDVI NEAWFPEDQR VLTPNLVAAL PPSTHGAGWQ LFCRTVWSAH SGPTRMATAI ARCAPDEELL SCSSFSRSGK RRGERMEAQG GKLVCRAHNA FGGEGVYAIA RCCLLPQANC SVHTAPPAEA SMGTRVHCHQ QGHVLTGCSS HWEVEDLGTH KPPVLRPRGQ PNQCVGHREA SIHASCCHAP GLECKVKEHG IPAPQEQVTV ACEEGWTLTG CSALPGTSHV LGAYAVDNTC VVRSRDVSTT GSTSEEAVTA VAICCRSRHL AQASQELQ

Produktmerkmale: Human PCSK9 full-length ORF (no protein_acc, 1 a.a. - 678 a.a.) recombinant protein with GST tag at N-terminal.

Aufreinigung: in vitro wheat germ expression system

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -80 °C

Informationen zur Lagerung: Best use within three months from the date of receipt of this protein.

Antigendetails

Target: PCSK9 (Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))

Andere Bezeichnung: PCSK9 (PCSK9 Produkte)

Synonyme: FH3 Protein, HCHOLA3 Protein, LDLCQ1 Protein, NARC-1 Protein, NARC1 Protein, PC9 Protein, AI415265 Protein, AI747682 Protein, Narc1 Protein, proprotein convertase subtilisin/kexin type 9 Protein, proprotein convertase subtilisin/kexin type 9 L homeolog Protein, PCSK9 Protein, pcsk9.L Protein, pcsk9 Protein, Pcsk9 Protein

Hintergrund: Synonyms: FH3,HCHOLA3,LDLCQ1,NARC-1,NARC1
Gene Description: proprotein convertase subtilisin/kexin type 9
Gene Name: PCSK9
Gene Summary: This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3).
GenBank: AK122717.1

Molekulargewicht: 99.2 kDa (theoreatical)

Gen-ID: 255738