FNDC5 Protein (AA 29-149, Extracellular Domain)
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- Target Alle FNDC5 Proteine anzeigen
- FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Extracellular Domain, AA 29-149
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Spezies
- Human, Maus, Ratte
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Quelle
- Escherichia coli (E. coli)
- Applikation
- SDS-PAGE (SDS)
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Produktmerkmale
- FNDC5 (extracellular domain, human (aa 32-152) / mouse (aa 29-149)) is untagged. FNDC5 extracellular domain has 100 % identity between human, mouse and rat.
- Reinheit
- >95 % (SDS-PAGE)
- Endotoxin-Niveau
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product FNDC5 Protein
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Fibronectin Type III Domain Containing 5 (FNDC5) (AA 1-137) protein (GST tag)
FNDC5 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Fibronectin Type III Domain Containing 5 (FNDC5) (AA 32-143) protein (His-IF2DI Tag)FNDC5 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Fibronectin Type III Domain Containing 5 (FNDC5) (AA 15-127) protein (His tag)FNDC5 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibronectin Type III Domain Containing 5 (FNDC5) (AA 14-78) protein (GST tag)FNDC5 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Fibronectin Type III Domain Containing 5 (FNDC5) protein (His tag)FNDC5 Spezies: Human, Maus, Ratte Wirt: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Fibronectin Type III Domain Containing 5 (FNDC5) (AA 2-137) (Active) protein (His tag)FNDC5 Spezies: Human Wirt: Escherichia coli (E. coli) > 90 % AcA, CC Active
Fibronectin Type III Domain Containing 5 (FNDC5) (AA 32-143) (Active) protein (His tag)FNDC5 Spezies: Human Wirt: HEK-293 Cells > 97 % AcA, CC Active
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute with 100 μL sterile water.
- Konzentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Haltbarkeit
- 6 months
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- Target
- FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))
- Andere Bezeichnung
- FNDC5 (FNDC5 Produkte)
- Synonyme
- FRCP2 Protein, irisin Protein, 1500001L03Rik Protein, AI836596 Protein, C87088 Protein, PeP Protein, Pxp Protein, fndc5 Protein, si:dkey-264p5.1 Protein, zgc:158684 Protein, fibronectin type III domain containing 5 Protein, fibronectin type III domain containing 5b Protein, FNDC5 Protein, Fndc5 Protein, fndc5b Protein
- Hintergrund
- Irisin is a recently described exercise and PGC1-alpha-induced myokine secreted by skeletal muscle in mice and humans. Irisin has been shown to induce browning of white adipose tissue, but this role has been questioned and a new function in the control of mass and strength of cortical bone has been reported. The membrane fibronectin type III domain containing protein 5 (FNDC5) can be cleaved by an unknown protease to release the Irisin protein (aa 32-143 for human) and potentially also the FNDC5 (extracellular domain, aa 32-153 for human).
- Molekulargewicht
- ~16kDa
- UniProt
- Q8NAU1
- Pathways
- Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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