VASP Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2735193

Produktdetails

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses VASP Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human VASP protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Andere Bezeichnung: Vasp (VASP Produkte)

Synonyme: vasp Protein, MGC80889 Protein, wu:fb23b04 Protein, wu:fk84g05 Protein, zgc:110347 Protein, si:dkey-113g17.1 Protein, si:ch211-202c21.1 Protein, DDBDRAFT_0188463 Protein, DDBDRAFT_0229340 Protein, DDB_0188463 Protein, DDB_0229340 Protein, VASP Protein, vasodilator stimulated phosphoprotein S homeolog Protein, vasodilator stimulated phosphoprotein b Protein, protein enabled Protein, vasodilator-stimulated phosphoprotein Protein, vasodilator stimulated phosphoprotein a Protein, vasodilator stimulated phosphoprotein Protein, vasp.S Protein, vaspb Protein, LOC5573842 Protein, CpipJ_CPIJ004706 Protein, CpipJ_CPIJ004707 Protein, vasP Protein, vasp Protein, VASP Protein, vaspa Protein, Vasp Protein

Hintergrund: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

Molekulargewicht: 39.6 kDa

NCBI Accession: NP_003361

Pathways: T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization, Tube Formation