USP8 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2735146

Produktdetails

Target: USP8 (Ubiquitin Specific Peptidase 8 (USP8))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses USP8 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human USP8 / UBPY (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: USP8 (Ubiquitin Specific Peptidase 8 (USP8))

Andere Bezeichnung: Usp8,ubpy (USP8 Produkte)

Synonyme: HumORF8 Protein, UBPY Protein, AI574262 Protein, AW557536 Protein, Ubpy Protein, mKIAA0055 Protein, ubiquitin carboxyl-terminal hydrolase 8 Protein, ubiquitin specific peptidase 8 Protein, LOC9310109 Protein, MGYG_00369 Protein, USP8 Protein, Usp8 Protein

Hintergrund: This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants.

Molekulargewicht: 127.3 kDa

NCBI Accession: NP_001122082