UGT1A8 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2734969

Produktdetails

Target: UGT1A8 (UDP Glucuronosyltransferase 1 Family, Polypeptide A8 (UGT1A8))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses UGT1A8 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human UDP glucuronosyltransferase 1 family, polypeptide A8 (UGT1A8) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: UGT1A8 (UDP Glucuronosyltransferase 1 Family, Polypeptide A8 (UGT1A8))

Abstract: UGT1A8 Produkte

Synonyme: UDPGT Protein, UDPGT 1-8 Protein, UGT-1H Protein, UGT1-08 Protein, UGT1.8 Protein, UGT1A8S Protein, UGT1H Protein, A116 Protein, OTTMUSG00000020811 Protein, Ugt1 Protein, Ugt1a9 Protein, UDP glucuronosyltransferase 1 family, polypeptide A8 Protein, UDP glucuronosyltransferase family 1 member A8 Protein, UDP glycosyltransferase 1 family, polypeptide A8 Protein, UGT1A8 Protein, Ugt1a8 Protein

Hintergrund: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5&apos exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity with many substrates including coumarins, phenols, anthraquinones, flavones, and some opioids.

Molekulargewicht: 57.1 kDa

NCBI Accession: NP_061949