SPHK2 Protein (Myc-DYKDDDDK Tag)
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- Target Alle SPHK2 Proteine anzeigen
- SPHK2 (Sphingosine Kinase 2 (SPHK2))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses SPHK2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human Sphingosine kinase 2 / SPK2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SPHK2 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SPHK2 (Sphingosine Kinase 2 (SPHK2))
- Andere Bezeichnung
- Sphingosine Kinase 2,spk2 (SPHK2 Produkte)
- Synonyme
- CG2159 Protein, CG32484 Protein, Dmel\\CG32484 Protein, SK2 Protein, Sphk2 Protein, sk2 Protein, DKFZp469F224 Protein, SK 2 Protein, SK-2 Protein, SPK 2 Protein, SPK-2 Protein, C76851 Protein, Sphingosine kinase Protein, sphk2 Protein, Sphingosine kinase 2 Protein, sphingosine kinase 2 Protein, sphK2 Protein, Sk2 Protein, SPHK2 Protein, Sphk2 Protein
- Hintergrund
- This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Molekulargewicht
- 69 kDa
- NCBI Accession
- NP_064511
- Pathways
- VEGF Signaling
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