SOCS5 Protein (His tag)

Produktnummer ABIN2732345

Produktdetails

Target: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SOCS5 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human SOCS5 / CIS6 (N-term HIS tag, transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))

Andere Bezeichnung: Socs5,cis6 (SOCS5 Produkte)

Synonyme: SOCS5 Protein, cis6 Protein, cish5 Protein, cish6 Protein, socs-5 Protein, GB18949 Protein, socs5 Protein, zgc:153506 Protein, CIS6 Protein, CISH6 Protein, Cish5 Protein, SOCS-5 Protein, 1810018L08Rik Protein, mKIAA0671 Protein, RGD1564914 Protein, suppressor of cytokine signaling 5 Protein, suppressor of cytokine signaling 5a Protein, suppressor of cytokine signaling 5 L homeolog Protein, SOCS5 Protein, socs5 Protein, LOC552036 Protein, socs5a Protein, Tsp_07018 Protein, socs5.L Protein, Socs5 Protein

Hintergrund: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.

Molekulargewicht: 61.1 kDa

NCBI Accession: NP_054730

Pathways: JAK-STAT Signalweg, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process