RHOC Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730853

Produktdetails

Target: RHOC (Ras Homolog Gene Family, Member C (RHOC))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RHOC Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RhoC (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RHOC (Ras Homolog Gene Family, Member C (RHOC))

Andere Bezeichnung: Rhoc (RHOC Produkte)

Synonyme: ARHC Protein, LOC100221682 Protein, ARH9 Protein, H9 Protein, RHOH9 Protein, AI324259 Protein, Arh9 Protein, Arhc Protein, CRHOC Protein, ras homolog family member C L homeolog Protein, ras homolog family member C Protein, rhoc.L Protein, RHOC Protein, rhoc Protein, Rhoc Protein

Hintergrund: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molekulargewicht: 21.8 kDa

NCBI Accession: NP_786886

Pathways: WNT Signalweg, Cell-Cell Junction Organization