RAD23B Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730408

Produktdetails

Target: RAD23B (RAD23 Homolog B (RAD23B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RAD23B Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RAD23B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RAD23B (RAD23 Homolog B (RAD23B))

Andere Bezeichnung: Rad23b (RAD23B Produkte)

Synonyme: HHR23B Protein, HR23B Protein, P58 Protein, 0610007D13Rik Protein, AV001138 Protein, mHR23B Protein, p58 Protein, MGC107846 Protein, zgc:65951 Protein, RAD23 homolog B, nucleotide excision repair protein Protein, UV excision repair protein RAD23 homolog B Protein, RAD23 homolog B, nucleotide excision repair protein S homeolog Protein, RAD23B Protein, Rad23b Protein, rd23b Protein, rad23b Protein, rad23b.S Protein

Hintergrund: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht: 43 kDa

NCBI Accession: NP_002865

Pathways: DNA Reparatur