PSMD2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2729996

Produktdetails

Target: PSMD2 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 2 (PSMD2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PSMD2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PSMD2 / TRAP2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PSMD2 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 2 (PSMD2))

Andere Bezeichnung: Psmd2,trap2 (PSMD2 Produkte)

Synonyme: DDBDRAFT_0192101 Protein, DDBDRAFT_0232978 Protein, DDB_0192101 Protein, DDB_0232978 Protein, zgc:65921 Protein, MGC83233 Protein, psmd2 Protein, MGC97650 Protein, PSMD2 Protein, P97 Protein, RPN1 Protein, S2 Protein, TRAP2 Protein, 9430095H01Rik Protein, AA407121 Protein, TEG-190 Protein, Tex190 Protein, 26S proteasome non-ATPase regulatory subunit 2 Protein, 26S proteasome regulatory subunit S2 Protein, proteasome 26S subunit, non-ATPase 2 Protein, proteasome 26S subunit, non-ATPase 2 L homeolog Protein, proteasome 26S subunit, non-ATPase 2 S homeolog Protein, proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 Protein, psmD2 Protein, NAEGRDRAFT_83014 Protein, DICPUDRAFT_55026 Protein, psmd2 Protein, psmd2.L Protein, psmd2.S Protein, PSMD2 Protein, Psmd2 Protein

Hintergrund: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. Alternative splicing results in multiple transcript variants of this gene.

Molekulargewicht: 100 kDa

NCBI Accession: NP_002799

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway