PSMA Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target Alle PSMA (FOLH1) Proteine anzeigen
- PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Transcript Variant 1
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses PSMA Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human PSMA / FOLH1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product FOLH1 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))
- Andere Bezeichnung
- Psma,folh1 (FOLH1 Produkte)
- Synonyme
- FGCP Protein, FOLH Protein, GCP2 Protein, GCPII Protein, NAALAD1 Protein, NAALAdase Protein, PSM Protein, PSMA Protein, mGCP Protein, mopsm Protein, Naalad Protein, putative N-acetylated-alpha-linked acidic dipeptidase Protein, folate hydrolase 1B Protein, folate hydrolase 1 Protein, folate hydrolase (prostate-specific membrane antigen) 1 Protein, LOC451185 Protein, FOLH1B Protein, FOLH1 Protein, Folh1 Protein
- Hintergrund
- This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants encoding several different isoforms.
- Molekulargewicht
- 84.2 kDa
- NCBI Accession
- NP_004467
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