PBX1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2729562

Produktdetails

Target: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PBX1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Pre-B-cell leukemia homeobox 1 (PBX1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PBX1 (Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))

Andere Bezeichnung: Pre-B-Cell Leukemia Homeobox 1 (Pbx1) (PBX1 Produkte)

Synonyme: fi29e01 Protein, pbx1b Protein, wu:fi29e01 Protein, zgc:55265 Protein, 2310056B04Rik Protein, AI848790 Protein, AU015730 Protein, D230003C07Rik Protein, Pbx-1 Protein, Pbx1a Protein, Pbx1b Protein, PBX1A Protein, Xpbx1 Protein, Xpbx1b Protein, PBX homeobox 1 Protein, pre-B-cell leukemia homeobox 1a Protein, pre B cell leukemia homeobox 1 Protein, pre-B-cell leukemia homeobox 1 S homeolog Protein, PBX1 Protein, pbx1a Protein, Pbx1 Protein, pbx1.S Protein

Hintergrund: This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(119) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 46.4 kDa

NCBI Accession: NP_002576