PBX1 Produkte
(Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
Kategorien
This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1\;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].
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Ausgewählte PBX1 Kategorien
PBX1 Antikörper
High quality antibodies with extensive validation data.
PBX1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PBX1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PBX1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC (p)
Validierungen
- (5)
- (5)
Kat. Nr.
ABIN562114
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7164137
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN571168
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene PBX1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1149119
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1149118
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PBX1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124544
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314106
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3094494
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PBX1 Produkten
: "The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1." in: Cell reports, Vol. 14, Issue 5, pp. 1156-1168, (2016) (PubMed).: "Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion." in: Nature communications, Vol. 6, pp. 10044, (2015) (PubMed).
: "Copy number aberrations of genes regulating normal thymus development in thymic epithelial tumors." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 8, pp. 1960-71, (2013) (PubMed).
: "Cooperative transcriptional activation by Klf4, Meis2, and Pbx1." in: Molecular and cellular biology, Vol. 31, Issue 18, pp. 3723-33, (2011) (PubMed).
: "PBX1 genomic pioneer function drives ER? signaling underlying progression in breast cancer." in: PLoS genetics, Vol. 7, Issue 11, pp. e1002368, (2011) (PubMed).
: "Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation." in: Human molecular genetics, Vol. 18, Issue 4, pp. 679-87, (2009) (PubMed).
: "Gfi1 integrates progenitor versus granulocytic transcriptional programming." in: Blood, Vol. 113, Issue 22, pp. 5466-75, (2009) (PubMed).
: "Evaluating the association of common PBX1 variants with type 2 diabetes." in: BMC medical genetics, Vol. 9, pp. 14, (2008) (PubMed).
: "Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer." in: Cancer research, Vol. 68, Issue 21, pp. 8852-60, (2008) (PubMed).
: "Pre-B-cell leukemia transcription factor 1 regulates expression of valosin-containing protein, a gene involved in cancer growth." in: The American journal of pathology, Vol. 170, Issue 1, pp. 152-9, (2007) (PubMed).
Synonyme und alternative Namen zu PBX1
PBX homeobox 1 (PBX1), pre-B-cell leukemia homeobox 1a (pbx1a), pre B cell leukemia homeobox 1 (Pbx1), PBX homeobox 1 (Pbx1), pre-B-cell leukemia homeobox 1 S homeolog (pbx1.S), 2310056B04Rik, AI848790, AU015730, D230003C07Rik, fi29e01, Pbx-1, Pbx1a, PBX1A, pbx1b, Pbx1b, wu:fi29e01, Xpbx1, Xpbx1b, zgc:55265Bezeichner auf Proteinebene für PBX1
- homeobox protein PBX1
- homeobox protein PRL
- pre-B-cell leukemia transcription factor 1
- pre-B-cell leukemia transcription factor 1b
- pre B-cell leukemia transcription factor 1
- Homeobox protein pbx1
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