PCBP1 Produkte
(Poly(rC) Binding Protein 1 (PCBP1))
Kategorien
This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. [provided by RefSeq, Jul 2008].
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Ausgewählte PCBP1 Kategorien
PCBP1 Antikörper
High quality antibodies with extensive validation data.
PCBP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PCBP1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PCBP1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Applikation
WB, IHC
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN2778971
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN518653
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (4)
Kat. Nr.
ABIN6145277
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PCBP1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969446
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1148571
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Cow
Analytical Method
Validierungen
Kat. Nr.
ABIN1148569
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PCBP1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124508
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314125
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314127
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PCBP1 Produkten
: "PCBP1/HNRNP E1 Protects Chromosomal Integrity by Translational Regulation of CDC27." in: Molecular cancer research : MCR, Vol. 14, Issue 7, pp. 634-46, (2016) (PubMed).: "Establishing an in vivo p48ZnF bioluminescence mouse brain imaging model." in: Neuroscience letters, Vol. 542, pp. 97-101, (2013) (PubMed).
: "Global analysis reveals multiple pathways for unique regulation of mRNA decay in induced pluripotent stem cells." in: Genome research, Vol. 22, Issue 8, pp. 1457-67, (2012) (PubMed).
: "PCBP1 is required for maintenance of the transcriptionally silent state in fully grown mouse oocytes." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 15, pp. 2833-42, (2012) (PubMed).
: "Depletion of the poly(C)-binding proteins alphaCP1 and alphaCP2 from K562 cells leads to p53-independent induction of cyclin-dependent kinase inhibitor (CDKN1A) and G1 arrest." in: The Journal of biological chemistry, Vol. 284, Issue 14, pp. 9039-49, (2009) (PubMed).
: "A cytosolic iron chaperone that delivers iron to ferritin." in: Science (New York, N.Y.), Vol. 320, Issue 5880, pp. 1207-10, (2008) (PubMed).
Synonyme und alternative Namen zu PCBP1
poly(rC) binding protein 1 (PCBP1), poly(rC) binding protein 1 L homeolog (pcbp1.L), poly(rC)-binding protein 1 (LOC100388387), poly(rC) binding protein 1 (Pcbp1), alphaCP-1, hnRNP-E1, hnRNP-X, hnRNP E1, HNRPE1, HNRPX, PCBP1, RGD1561319, WBP17, [a]CP-1Bezeichner auf Proteinebene für PCBP1
- poly(rC) binding protein 1
- poly(rC)-binding protein 1-like
- alpha-CP1
- heterogeneous nuclear ribonucleoprotein E1
- heterogenous nuclear ribonucleoprotein E1
- heterogenous nuclear ribonucleoprotein X
- nucleic acid-binding protein SUB2.3
- poly(rC)-binding protein 1
- hnRNP-E1 protein
- hnRNP E1
- hnRNP-E1
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