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PBK Produkte

(PDZ Binding Kinase (PBK))
This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. [provided by RefSeq, Jul 2008].

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Ausgewählte PBK Kategorien

PBK Antikörper

High quality antibodies with extensive validation data.

PBK ELISA Kits

Reliable ELISA kits for a wide range of species.

PBK Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PBK Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS, ICC
Validierungen
  • (2)
  • (7)
Kat. Nr. ABIN969345
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p), IF
Validierungen
  • (7)
Kat. Nr. ABIN527757
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p), FACS
Validierungen
  • (2)
  • (4)
Kat. Nr. ABIN1881635
Menge 400 μL
Datenblatt Datenblatt

Empfohlene PBK ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951206
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380317
Menge 2 x 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1141112
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PBK Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect cells (Sf21)
Validierungen
  • (2)
Kat. Nr. ABIN5569604
Menge 5 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect cells (Sf9)
Validierungen
  • (2)
Kat. Nr. ABIN5569603
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124331
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PBK Produkten

Park, Nishidate, Nakamura, Katagiri: "Critical roles of T-LAK cell-originated protein kinase in cytokinesis." in: Cancer science, Vol. 101, Issue 2, pp. 403-11, (2010) (PubMed).

Mulder, Björling, Jonasson, Wernérus, Hober, Hökfelt, Uhlén: "Tissue profiling of the mammalian central nervous system using human antibody-based proteomics." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 7, pp. 1612-22, (2009) (PubMed).

Oh, Zhu, Cho, Lee, Kang, Kim, Zykova, Bode, Dong: "T-lymphokine-activated killer cell-originated protein kinase functions as a positive regulator of c-Jun-NH2-kinase 1 signaling and H-Ras-induced cell transformation." in: Cancer research, Vol. 67, Issue 11, pp. 5186-94, (2007) (PubMed).

Zykova, Zhu, Lu, Higgins, Tatsumi, Abe, Bode, Dong: "Lymphokine-activated killer T-cell-originated protein kinase phosphorylation of histone H2AX prevents arsenite-induced apoptosis in RPMI7951 melanoma cells." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 23, pp. 6884-93, (2006) (PubMed).

Fujibuchi, Abe, Takeuchi, Ueda, Shigemoto, Yamamoto, Kito: "Expression and phosphorylation of TOPK during spermatogenesis." in: Development, growth & differentiation, Vol. 47, Issue 9, pp. 637-44, (2005) (PubMed).

Nandi, Tidwell, Karp, Rapoport: "Protein expression of PDZ-binding kinase is up-regulated in hematologic malignancies and strongly down-regulated during terminal differentiation of HL-60 leukemic cells." in: Blood cells, molecules & diseases, Vol. 32, Issue 1, pp. 240-5, (2004) (PubMed).

Simons-Evelyn, Bailey-Dell, Toretsky, Ross, Fenton, Kalvakolanu, Rapoport: "PBK/TOPK is a novel mitotic kinase which is upregulated in Burkitt's lymphoma and other highly proliferative malignant cells." in: Blood cells, molecules & diseases, Vol. 27, Issue 5, pp. 825-9, (2002) (PubMed).

Zhao, Dai, Zhao, Xia, Zhou, Wang, Gu, Ying, Xie, Mao: "PDZ-binding kinase participates in spermatogenesis." in: The international journal of biochemistry & cell biology, Vol. 33, Issue 6, pp. 631-6, (2001) (PubMed).

Abe, Matsumoto, Kito, Ueda: "Cloning and expression of a novel MAPKK-like protein kinase, lymphokine-activated killer T-cell-originated protein kinase, specifically expressed in the testis and activated lymphoid cells." in: The Journal of biological chemistry, Vol. 275, Issue 28, pp. 21525-31, (2000) (PubMed).

Gaudet, Branton, Lue: "Characterization of PDZ-binding kinase, a mitotic kinase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 10, pp. 5167-72, (2000) (PubMed).

Synonyme und alternative Namen zu PBK

PDZ binding kinase (PBK), PDZ binding kinase (pbk), PDZ binding kinase (Pbk), PDZ binding kinase L homeolog (pbk.L), 2810434B10Rik, AW538537, CT84, D14Ertd732e, Nori-3, PBK, SPK, topk, TOPK, zgc:92050

Bezeichner auf Proteinebene für PBK

  • PDZ binding kinase
  • T-LAK cell-originated protein kinase
  • MAPKK-like protein kinase
  • cancer/testis antigen 84
  • lymphokine-activated killer T-cell-originated protein kinase
  • serine/threonine protein kinase
  • spermatogenesis-related protein kinase
  • PDZ-binding kinase
  • PBK, PDZ-binding kinase
  • lymphokine-activated killer T-cell-originated protein kinase homolog
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