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PAX8 Produkte

(Paired Box 8 (PAX8))
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010].

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Ausgewählte PAX8 Kategorien

PAX8 Antikörper

High quality antibodies with extensive validation data.

PAX8 ELISA Kits

Reliable ELISA kits for a wide range of species.

PAX8 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PAX8 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF, IHC (p), IP, ICC, ChIP
Validierungen
  • (2)
  • (8)
Kat. Nr. ABIN2855097
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS
Validierungen
  • (7)
Kat. Nr. ABIN7193697
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, FACS, IF, StM
Validierungen
  • (6)
Kat. Nr. ABIN6940924
Menge 100 μg
Datenblatt Datenblatt

Empfohlene PAX8 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969128
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validierungen
Kat. Nr. ABIN5648503
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6951205
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PAX8 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN2752880
Menge 2 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124298
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1314083
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PAX8 Produkten

Shi, Yin, Cai, Yan, Jia, Ma, Zhang, Zhang, Gu, Zhang, Di, Zhuang: "PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors." in: eLife, Vol. 8, (2020) (PubMed).

Sun, Lu, Wu, Ouyang, Xing, Hou, Shi, Wu: "PTEN-knockdown disrupts the morphology, growth pattern and function of Nthy-Ori 3-1 cells by downregulating PAX8 expression." in: Oncology letters, Vol. 18, Issue 6, pp. 6732-6740, (2019) (PubMed).

Kang, Kumar, Liao, Lichti-Kaiser, Gerrish, Liao, Refetoff, Jothi, Jetten: "GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation." in: The Journal of clinical investigation, (2018) (PubMed).

Adler, Corona, Lee, Rodriguez-Malave, Mhawech-Fauceglia, Sowter, Hazelett, Lawrenson, Gayther: "The PAX8 cistrome in epithelial ovarian cancer." in: Oncotarget, Vol. 8, Issue 65, pp. 108316-108332, (2018) (PubMed).

di Martino, De Luca, Grassi, Federici, Alfonsi, Signore, Addario, De Salvo, Francescangeli, Sanchez, Tirelli, Muto, Sperduti, Sentinelli, Costantini, Pasquini, Milella, Haoui, Simone, Gallucci et al.: "Renal cancer: new models and approach for personalizing therapy. ..." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 217, (2018) (PubMed).

Ludwig, Alaggio, Zin, Peron, Guzzardo, Benini, Righi, Gambarotti: "BCOR-CCNB3 Undifferentiated Sarcoma-Does Immunohistochemistry Help in the Identification?" in: Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, Vol. 20, Issue 4, pp. 321-329, (2017) (PubMed).

Elias, Emori, Westerling, Long, Budina-Kolomets, Li, MacDuffie, Davis, Holman, Lawney, Freedman, Quackenbush, Brown, Drapkin: "Epigenetic remodeling regulates transcriptional changes between ovarian cancer and benign precursors." in: JCI insight, Vol. 1, Issue 13, (2016) (PubMed).

Imberti, Tomasoni, Ciampi, Pezzotta, Derosas, Xinaris, Rizzo, Papadimou, Novelli, Benigni, Remuzzi, Morigi: "Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury." in: Scientific reports, Vol. 5, pp. 8826, (2015) (PubMed).

McKnight, Cohen, Siddiqui: "Utility of paired box gene 8 (PAX8) expression in fluid and fine-needle aspiration cytology: an immunohistochemical study of metastatic ovarian serous carcinoma." in: Cancer cytopathology, Vol. 118, Issue 5, pp. 298-302, (2010) (PubMed).

Chia, Sharifah, Reena, Zubaidah, Clarence-Ko, Rohaizak, Naqiyah, Srijit, Hisham, Asmiati, Rafie: "Fluorescence in situ hybridization analysis using PAX8- and PPARG-specific probes reveals the presence of PAX8-PPARG translocation and 3p25 aneusomy in follicular thyroid neoplasms." in: Cancer genetics and cytogenetics, Vol. 196, Issue 1, pp. 7-13, (2009) (PubMed).

Synonyme und alternative Namen zu PAX8

paired box 8 (PAX8), paired box 8 (pax8), paired box 8 (Pax8), paired box 8 L homeolog (pax8.L), pax-8, PAX-8, Pax-8, PAX8, XPax-8, XPax8

Bezeichner auf Proteinebene für PAX8

  • paired box 8
  • paired box gene 8
  • paired box protein Pax-8
  • paired domain gene 8
  • Pax-8 protein
  • Pax-8 DNA-binding transcription factor
  • XPax-8
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