PPP1R12B Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2729470

Produktdetails

Target: PPP1R12B (Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 4

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PPP1R12B Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PPP1R12B / MYPT2 (transcript variant 4) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PPP1R12B (Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))

Andere Bezeichnung: Ppp1r12b,mypt2 (PPP1R12B Produkte)

Synonyme: 1810037O03Rik Protein, 9530009M10Rik Protein, AI132431 Protein, Mypt2 Protein, MYPT2 Protein, PP1bp55 Protein, protein phosphatase 1, regulatory subunit 12B Protein, protein phosphatase 1, regulatory (inhibitor) subunit 12B Protein, protein phosphatase 1 regulatory subunit 12B Protein, Ppp1r12b Protein, PPP1R12B Protein

Hintergrund: Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome.

Molekulargewicht: 26.1 kDa

NCBI Accession: NP_115287

Pathways: M Phase