POLD2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2729300

Produktdetails

Target: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses POLD2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human POLD2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Andere Bezeichnung: Pold2 (POLD2 Produkte)

Synonyme: 50kDa Protein, p50 Protein, po1D2 Protein, cdc1 Protein, si:dz150f13.3 Protein, zgc:55633 Protein, zgc:77043 Protein, DNA polymerase delta 2, accessory subunit Protein, polymerase (DNA directed), delta 2, regulatory subunit Protein, polymerase (DNA directed), delta 2, accessory subunit L homeolog Protein, POLD2 Protein, Pold2 Protein, pold2.L Protein, pold2 Protein

Hintergrund: This gene encodes the 50- kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.

Molekulargewicht: 51.1 kDa

NCBI Accession: NP_006221

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA