PLA2G4A Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2729077

Produktdetails

Target: PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PLA2G4A Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PLA2G4A protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))

Andere Bezeichnung: Pla2g4a (PLA2G4A Produkte)

Synonyme: PLA2G4 Protein, cPLA2-alpha Protein, Pla2c Protein, Pla2g4 Protein, cPLA2 Protein, pla2g4 Protein, CPLA2 Protein, PLA2G4A Protein, PLA2 Protein, PLA2G1B Protein, cPLA2alpha Protein, pla2g4a Protein, si:dkey-97o5.1 Protein, phospholipase A2 group IVA Protein, phospholipase A2 group IVA L homeolog Protein, phospholipase A2, group IVA (cytosolic, calcium-dependent) Protein, phospholipase A2, group IVAb (cytosolic, calcium-dependent) Protein, PLA2G4A Protein, Pla2g4a Protein, pla2g4a.L Protein, pla2g4ab Protein

Hintergrund: This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 85 kDa

NCBI Accession: NP_077734

Pathways: Inositol Metabolic Process, G-protein mediated Events, VEGF Signaling