PDCD6 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2728465

Produktdetails

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PDCD6 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PDCD6 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Andere Bezeichnung: Pdcd6 (PDCD6 Produkte)

Synonyme: pdcd6 Protein, MGC52821 Protein, MGC132114 Protein, zgc:63952 Protein, PDCD6 Protein, ALG-2 Protein, PEF1B Protein, AV299538 Protein, Alg2 Protein, MA-3 Protein, PS2 Protein, alg-2 Protein, programmed cell death 6 L homeolog Protein, programmed cell death 6 Protein, pdcd6.L Protein, pdcd6 Protein, PDCD6 Protein, Pdcd6 Protein

Hintergrund: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

Molekulargewicht: 21.7 kDa

NCBI Accession: NP_037364

Pathways: Positive Regulation of Endopeptidase Activity