PDCD6 Protein (AA 1-191, full length) (GST tag)

Produktnummer ABIN1047560

Produktdetails

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-191, full length

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PDCD6 Protein ist gelabelt mit GST tag.

Applikation: ELISA

Sequenz: MAAYSYRPGP GAGPGPAAGA ALPDQSFLWN VFQRVDKDRS GVISDTELQQ ALSNGTWTPF NPVTVRSIIS MFDRENKAGV NFSEFTGVWK YITDWQNVFR TYDRDNSGMI DKNELKQALS GFGYRLSDQF HDILIRKFDR QGRGQIAFDD FIQGCIVLQR LTDIFRRYDT DQDGWIQVSY EQYLSMVFSI V

Produktmerkmale: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Reinheit: 90 %

Anwendungsinformationen

Kommentare:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handhabung: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

Referenzen

Kitaura, Satoh, Takahashi, Shibata, Maki: "Both ALG-2 and peflin, penta-EF-hand (PEF) proteins, are stabilized by dimerization through their fifth EF-hand regions." in: Archives of biochemistry and biophysics, Vol. 399, Issue 1, pp. 12-8, (2002) (PubMed).

Kitaura, Matsumoto, Satoh, Hitomi, Maki: "Peflin and ALG-2, members of the penta-EF-hand protein family, form a heterodimer that dissociates in a Ca2+-dependent manner." in: The Journal of biological chemistry, Vol. 276, Issue 17, pp. 14053-8, (2001) (PubMed).

Antigendetails

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Andere Bezeichnung: Programmed cell death protein 6 protein (PDCD6 Produkte)

Synonyme: pdcd6 Protein, MGC52821 Protein, MGC132114 Protein, zgc:63952 Protein, PDCD6 Protein, ALG-2 Protein, PEF1B Protein, AV299538 Protein, Alg2 Protein, MA-3 Protein, PS2 Protein, alg-2 Protein, programmed cell death 6 L homeolog Protein, programmed cell death 6 Protein, pdcd6.L Protein, pdcd6 Protein, PDCD6 Protein, Pdcd6 Protein

Hintergrund: Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca2+-regulated signals along the death pathway By similarity. Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101.

Molekulargewicht: 49.3 kD

UniProt: O75340

Pathways: Positive Regulation of Endopeptidase Activity