PCBP1 Protein (Myc-DYKDDDDK Tag)
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- Target Alle PCBP1 Proteine anzeigen
- PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses PCBP1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human PCBP1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PCBP1 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PCBP1 (Poly(rC) Binding Protein 1 (PCBP1))
- Andere Bezeichnung
- Pcbp1 (PCBP1 Produkte)
- Synonyme
- PCBP1 Protein, HNRPE1 Protein, HNRPX Protein, hnRNP-E1 Protein, hnRNP-X Protein, hnRNP E1 Protein, WBP17 Protein, [a]CP-1 Protein, alphaCP-1 Protein, RGD1561319 Protein, poly(rC) binding protein 1 Protein, poly(rC) binding protein 1 L homeolog Protein, poly(rC)-binding protein 1 Protein, PCBP1 Protein, pcbp1.L Protein, LOC100388387 Protein, Pcbp1 Protein
- Hintergrund
- This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
- Molekulargewicht
- 37.3 kDa
- NCBI Accession
- NP_006187
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