MYBL2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2726621

Produktdetails

Target: MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MYBL2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human MYBL2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: MYBL2 (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2))

Andere Bezeichnung: Mybl2 (MYBL2 Produkte)

Synonyme: MYBL2 Protein, bmyb Protein, b-myb Protein, B-Myb Protein, Bmyb Protein, B-MYB Protein, BMYB Protein, myb1 Protein, MYB proto-oncogene like 2 Protein, v-myb avian myeloblastosis viral oncogene homolog-like 2b Protein, myeloblastosis oncogene-like 2 Protein, MYB proto-oncogene like 2 S homeolog Protein, MYBL2 Protein, mybl2 Protein, mybl2b Protein, Mybl2 Protein, mybl2.S Protein

Hintergrund: The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 78.6 kDa

NCBI Accession: NP_002457

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, Chromatin Binding